Copper-Catalyzed Hydroarylation of Alkynes for the Synthesis of Fascaplysin, Rutacarpine and Granulatimide Analogues

Abstract

An efficient copper-catalyzed π-activation protocol has been developed for the intramolecular hydroarylation of alkynes. The strategy has been used in atom-economical syntheses of β-carboline analogues. The cycloisomerized products were obtained in moderate to good yields.

Key words

arylations - cyclizations - alkynes - carbolines

• References

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